Mae Trystan Bevan, sy'n ffermio yn Eryri, yn benderfynol o reoli plau
ar dir ffermio a thir agored.
As reported in Table 2, 14 genes (KRT19, FLT1, EGER, EPCAM, MET, PGR, CD24, KIT, PLAU
, ALDH1A1, CTSD, MKI67, TWIST1, and ERBB2) were evaluated as significantly differentially expressed in the tested sample cohorts between CTC+ and CTC- samples.
Struhl, "Inhibition of miR193a expression by Max and RXR[alpha] activates K-Ras and PLAU
to mediate distinct aspects of cellular transformation," Cancer Research, vol.
Matrix degradation- and endothelial cell migration-related factors were up-regulated, including: MMP2 (fold change, 4.0), MMP9 (fold change, 4.2), TIMP2 (fold change, 5), PLG (fold change, 2.5) and PLAU
(fold change, 6).
They demonstrated that these high levels of miR-198 prevent skin cell migration by suppressing several genes, such as PLAU
, LAMC2 and DIAPH1(4), which are needed for different aspects of the wound healing process.
Gene analysis confirmed that the breast formula down-regulated genes associated with breast cancer proliferation and metastasis, such as PLAU
(urokinase plasminogen activator, uPA) and CXCR4 (C-X-C chemokine receptor-4).
The next morning, we left for Plau
am See which, as its name suggests, lies on the bank of a lake.
am See, as its name suggests, lies on the bank of a lake.
The area is steeped in history, the medieval town of Plau
is well worth a visit with its 15th century castle giving impressive views over tiled roofs and fortifications.