Mae Trystan Bevan, sy'n ffermio yn Eryri, yn benderfynol o reoli
plau ar dir ffermio a thir agored.
As reported in Table 2, 14 genes (KRT19, FLT1, EGER, EPCAM, MET, PGR, CD24, KIT,
PLAU, ALDH1A1, CTSD, MKI67, TWIST1, and ERBB2) were evaluated as significantly differentially expressed in the tested sample cohorts between CTC+ and CTC- samples.
Struhl, "Inhibition of miR193a expression by Max and RXR[alpha] activates K-Ras and
PLAU to mediate distinct aspects of cellular transformation," Cancer Research, vol.
Matrix degradation- and endothelial cell migration-related factors were up-regulated, including: MMP2 (fold change, 4.0), MMP9 (fold change, 4.2), TIMP2 (fold change, 5), PLG (fold change, 2.5) and
PLAU (fold change, 6).
They demonstrated that these high levels of miR-198 prevent skin cell migration by suppressing several genes, such as
PLAU, LAMC2 and DIAPH1(4), which are needed for different aspects of the wound healing process.
Gene analysis confirmed that the breast formula down-regulated genes associated with breast cancer proliferation and metastasis, such as
PLAU (urokinase plasminogen activator, uPA) and CXCR4 (C-X-C chemokine receptor-4).
The next morning, we left for
Plau am See which, as its name suggests, lies on the bank of a lake.
Plau am See, as its name suggests, lies on the bank of a lake.
The area is steeped in history, the medieval town of
Plau is well worth a visit with its 15th century castle giving impressive views over tiled roofs and fortifications.