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PLUNCPalate Lung and Nasal Epithelial Clone (gene)
PLUNCPlanning Land Use & Neighborhoods Committee (Seattle, WA)
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References in periodicals archive ?
SPLUNC1 (PLUNC) is expressed in glandular tissues of the respiratory tract and in lung tumours with a glandular phenotype.
PLUNC (palate, lung and nasal epithelial clone) proteins in human nasal lavage fluid.
Expression of PLUNC family members in benign and malignant salivary gland tumours.
(9,10,11,12) Expression and localization of the proteins in developing tissues has been given little attention since the first description of BPIFA1 (PLUNC) by Weston et al.
Phylogenetic and evolutionary analysis of the PLUNC gene family.
PLUNC: a novel family of candidate host defense proteins expressed in the upper airways and nasopharynx.
McCray, "PLUNC is a secreted product of neutrophil granules," Journal of Leukocyte Biology, vol.
Lindahl, "PLUNC in human nasal lavage fluid: multiple isoforms that bind to lipopolysaccharide," Biochimica et Biophysica Acta, vol.
PLUNC genes are expressed predominantly in the upper respiratory tract, nasal mucosa, and oral cavity.
PLUNC mRNA has been identified in upper airways mucosa and also the proteins were localized to the same sites too, while their expression is absent in small airways and peripheral lung.
We selected the novel secretory PLUNC protein for immunohistochemical analysis in paraffin-embedded tissue samples to validate the differential expression among nasal polyps, chronic sinusitis, and normal nasal mucosal tissue, and to observe the localization of its expression in tissues and cells.
To ascertain the intensity of PLUNC protein expression, we cut the paraffin-embedded tissue blocks into 4-[micro]m-thick sections, which were then deparaffinized, dehydrated through a graded alcohol series, rehydrated, and subjected to antigen recovery by autoclaving.