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Inhaled therapy is the gold standard for treatment of asthma  and chronic obstructive pulmonary disease (COPD)  in patients treated with pressurized metered-dose inhalers (pMDIs).
In the manufacturing of pMDIs, developers have two major approaches to choose from: cold filling and pressure filling.
(11,19) Several studies have demonstrated fewer inhalation errors with DPIs compared with pMDIs. (22,26-28)
* Landmark, an award-winning integrated dose indicator for pressurized metered dose inhalers (pMDIs), has been developed in compliance with FDA guidance to integrate a dose-counting mechanism into pMDI drug products.
When using pMDIs, slow inhalation (over 4-5 seconds in an adult) after a deep exhalation helps to minimize such deposition in the upper airway and enhance delivery of the drug to the lungs.
Aerosol therapy may be administered to a patient receiving NIV through pMDIs or nebulizers [64-67].
), compared with most pMDIs and DPIs as well as to provide increased flexibility for synchronization between actuation and inhalation through the slow movement of the mist generated [38, 39].
Pharmaterials provides complete formulation services for inhaled drug delivery using dry powder inhaler (DPI) and pressurized metered dose inhaler (pMDI) systems.
The company has a wealth of experience in the development of low solubility drug substances and provide a complete formulation service for inhaled drug delivery using dry powder inhaler (DPI) and pressurized metered dose inhaler (pMDI) systems.
The ultra thin coating is suitable for both plastics and metals, and addresses several existing challenges with pMDI hard ware, according to the company.
Nebulizers and pMDIs are employed to deliver aerosolized medications to patients receiving NIV.
Many patients find pMDIs difficult to use correctly.
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- PMD Cloud-Recognition Algorithm
- PMEL Automated Management System