POLHPrairie Outpost Log Homes (North Dakota)
POLHPolymerase, DNA, ETA
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References in periodicals archive ?
There are reports about the popular use of Tapinanthus dodoneifolius (DC) Danser (Loranthaceae) also called Agelanthus dodoneifolius (Polh and Wiens) in treating hypertension [11] and malaria [12].
A human POLH (which encodes Pol [beta]) cDNA was amplified via PCR from a cDNA template isolated from HEK293 cells; KOD-Plus-Neo (TOYOBO) and two POLH-specific primers (XhoI-linked forward primer, 5'-TACTCGAGATGGCTACTGGACAGGATCGAGTG-3', and XhoI-linked reverse primer, 5,-TACTCGAGCTAATGTGTTAATGGCTTAAAAAA-37; XhoI sites are underlined) were used for amplification.
This intriguing finding leads to the hypothesis that the Polh gene, which encodes Pol [eta], evolved specifically to relieve replicative arrest associated with the presence of unexcised pyrimidine dimers in DNA following exposure of cells to UV radiation--and does so accurately.