This was a 4-week pre- and postintervention study investigating the effects of pomegranate polyphenol supplementation (POMx capsules, Pom Wonderful, CA, USA), in subjects with T2DM and in healthy volunteers.
The participants were supplemented with a daily dose of two POMx capsules (1 capsule = 753 mg polyphenols) for a period of four weeks.
Table 1 shows the nutritional composition of the POMx supplementation.
As shown in Table 3, POMx supplementation did not significantly affect glucose, HbA1c, blood pressure, and lipids at 4 weeks versus baseline in healthy controls as well as in T2DM patients.
Our pre- and postintervention data analyses show that POMx supplementation (2 capsules/day ~1500 mg polyphenols) did not significantly alter safety parameters in both groups of participants.
In one of last year's major legal actions, "as part of its ongoing efforts to uncover over-hyped health claims in food advertising," the FTC issued an administrative complaint charging the makers of POM Wonderful 100% Pomegranate Juice and POMx
supplements with making false and unsubstantiated claims that their products could prevent or treat heart disease, prostate cancer and erectile dysfunction, according to the FTC website.
High antioxidant levels and/or superfruit ingredients (Examples: PomX Antioxidant Superbar, Nutri-Grain Superfruit Fusion)
Stepping outside of the beverage world, POM Wonderful, Los Angeles, CA, introduced Antioxidant Superbars Dipped in Chocolate, which contain POMx, "an ultra-potent natural antioxidant." In addition to being natural, the company says the bars are gluten-free and made with real fruits and nuts.
Polyphenol-rich pomegranate fruit extract (POMx
) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-kappaB in human KU812 cells.
POM Wonderful, Los Angeles, CA, debuted POMx
Antioxidant Recovery, which contains a combination of concentrated POM Wonderful 100% pomegranate juice and POMx
However, no studies have been undertaken to investigate whether a polyphenol-rich pomegranate fruit extract (POMx
) inhibits the inflammatory activity of activated human mast cells and basophils.
"keepsake" glass bottle with a "lid-style closure." According to company literature, it contains POMx
, a highly-concentrated (and powerful) blend of polyphenol antioxidants.