POT1


Also found in: Medical.
AcronymDefinition
POT1Protection of Telomeres 1 (protein)
References in periodicals archive ?
The study has found that people with specific mutations in the POT1 gene were extremely likely to develop melanoma and these mutations deactivate the gene that protects the ends of our chromosomes from damage.
Researchers revealed that the inactivation of POT1 caused by these mutations leads to longer and potentially unprotected telomeres, regions at the end of our chromosomes that protect chromosomes from damage.
University of Michigan, Ann Arbor, MI, "Structural studies of single-stranded telomeric DNA and its binding protein POT1.