POTPPop on the Pop (website)
POTPPower of the Pen
POTPPicnic on the Pyre (band)
POTPProfessor of the Practice (Carnegie-Mellon University School of Computer Science; Pittsburgh, PA)
POTPPart Of The Problem (World of Warcraft guild)
POTPPieces of the Puzzle (Harry Potter fanfiction)
POTPParty on the Potomac (boating club)
POTPPacket Optical Transport Platform
POTPPoint Therapeutics (stock symbol)