PPAR


Also found in: Medical.
AcronymDefinition
PPARPeroxisome Proliferator Activated Receptor
PPARPikes Peak Association of Realtors (Colorado Springs, CO)
PPARPaw Prints Animal Rescue (Garner, NC)
PPARPharmaceutical Process Analytics Roundtable
PPARPeripheral Pulse Amplitude Response (physiology)
PPARPhenomenon of Predominant Activation of Relaxation
References in periodicals archive ?
Interplay between statins and PPARs in improving cardiovascular outcomes: a double edged sword?
Rifaai, "Peroxisome proliferator activator receptor (PPAR)-[gamma] ligand, but not PPAR-[alpha], ameliorates cyclophosphamide-induced oxidative stress and inflammation in rat liver," PPAR Research, vol.
The LBE treated cells showed a specific increase in expression of PPAR target gene expression, including fatty acid binding protein 4, fatty acid transport protein 4, CD36 molecule, pyruvate dehydrogenase kinase 4, liver X receptor alpha and lipogenic stearoyl-CoA desaturase.
These results also provide a new rationale for developing therapeutics that could block PPAR delta to treat inflammatory bowel disease and colorectal cancer," he said.
We will focus on the premise that PPAR activation is indeed anti-inflammatory and has therapeutic benefit.
In vitro PPAR activity of nutmeg seeds was measured using a GAL4/PPAR chimera & reported gene
These beneficial effects on glucose and lipids were observed without causing the weight gain which has been seen with other PPAR agonists.
The second drug candidate DB959 is a highly selective, non-thiazolidinedione (TZD), first-in-class dual PPAR (peroxisome proliferator activated receptor) delta/gamma agonist in development for type II diabetes.
For example, GlaxoSmithKline Plc's diabetes drug Avandia, known generically as rosiglitazone, has been shown to restore gut defenses through PPAR-gamma activation, he said, and Takeda Pharmaceutical's Actos, or pioglitazone, another PPAR drug