Peroxisome Proliferators-Activated Receptor (
PPAR) Modulators and Metabolic Disorders.
PPAR Res 2017:6139107, PMID: 29225614, https://doi.org/10.1155/2017/6139107.
Our findings as a whole imply that treatment with a dual
PPAR?/?
Galli, "PPAR[gamma] and oxidative stress: Con([beta]) catenating NRF2 and FOXO,"
PPAR Research, vol.
However, its expression as measured by mRNA levels is elevated in AD patients, suggesting that
PPAR may play a crucial role in modulating the pathology of AD [94].
Wong, "Current understanding of the role of PPARgamma in gastrointestinal cancers,"
PPAR Research, vol.
Considering the relevance of CD36 receptor to metabolism and accumulation of lipids in macrophages and previous reports demonstrating that this receptor is under transcriptional control of
PPAR family [27], we evaluated the participation of PPAR-[gamma] and PPAR-[beta]/[delta] in the upregulation of CD36 expression induced by MT-III.
Chawla, "Control of macrophage activation and function by
PPARs," Circulation Research, vol.
Effects of
PPAR? agonist pioglitazone on coronary atherosclerotic plaque composition and plaque progression in non diabetic patients: double centered randomized controlled VH-IVUS pilot trial.
In whole thiazolidinediones possess a large structure which enables them to bind to the polar as well as the big hydrophobic binding pockets of the ligand binding domain of
PPAR. The linker (L1) between the central phenyl ring and the thiazolidinedione is at its best if it has one carbon atom.
Robker, "Regulation of fatty acid oxidation in mouse cumulus-oocyte complexes during maturation and modulation by
PPAR agonists," PLoS One, vol.
Moreover, MDA (malondialdehyde) level, catalase activity, levels of insulin and
PPAR)' mRNA expression were also measured in pancreatic tissue.
