Measure Staff Survey Qualitative Inquiry Survey Response by PRC, % (n) PRC1
Keeping cell identity in Arabidopsis requires PRC1
RING-finger homologs that catalyze H2A monoubiquitination.
In short, SUMO helps the PRC1
complex repress genes, and SENP2 reverses this repression, allowing gene transcription and expression.
PRC2 has similar repressive properties to PRC1 and also is an essential regulator of cellular differentiation.
However, compared with the PRC1 and PRC2 complexes, very little information exists on individual TrxG proteins or their biochemical functions (Schuettengruber et al.
Our results show that Fbxl10 is essential for recruiting PRC1
to genes that are to be silenced in embryonic stem cells.
Both presentations will be held during Session PRC1
, titled Radiography Techniques for Inspection of Advanced Electronic Packages, and will take place Tuesday, Sept.
Researchers at the Centre for Genomic Regulation (CRG, Barcelona, Spain) have now elucidated the role that several specific Polycomb proteins (namely, Cbx2, -4, -6, -7, and -8) play during cell development through their incorporation into, and regulation by, the PRC1 complex.
The discovery helps understand how stem cells proliferate and which specific functions the Cbx proteins and the Polycomb PRC1 complex play during tumor development.