PREOSPrediction of Performance & Range for Electro-Optical Systems
PREOSPeng-Robinson Equation of State (chemical engineering)
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The new 2-year data show that women who followed Preos therapy with Fosamax continued gaining lumbar spine bone density, for an overall gain of 12%, compared with baseline (N.
Francois has brought strong management, strategic and clinical experience to NPS and his contributions as a director will be invaluable as we work to develop and gain approval for our most important assets, GATTEX and PREOS.
Specifically, Defendants concealed: (1) results of the PaTH study evidenced that PEROS was not different from Fosamax in both bone density and fracture results; (2) there was a very small market for this type of drug; (3) a major study concluded that more studies would be needed to determine efficacy; and, (4) PREOS could not be prescribed for broader fracture uses.
executive vice president and chief operating officer, stated: "Alan brings impressive credentials and industry experience to NPS and will play a critical role in leading the company's research and development programs for GATTEX, PREOS and NPSP156.
Completed the Phase 3 study of GATTEX in short bowel syndrome and announced top-line results in October; -- Secured a development and commercialization partner for one of its late-stage programs; -- Monetized non-core assets to raise cash; -- Retired substantially all of its 2008 convertible debt; -- Reduced cash burn guidance to $70 to $80 million from previous guidance of $80 to $90 million; -- Positioned the company to burn between $35 and $45 million in 2008; -- Explored the development of PREOS and GATTEX in at least one new indication for each program.
This strategic move creates investment flexibility for NPS and enables us to use the monies from this deal, the previously announced Nycomed GATTEX deal and the approximately $10 million in savings over the next two years from this transaction to support the further development of our late-stage pipeline products, PREOS and GATTEX, in specialty indications.
The upgrade came as a result of recent due diligence which Lehman believes suggests an improved risk/reward profile on the regulatory review and commercial potential of NPSP's osteoporosis drug Preos.
PREOS could potentially be a first-in-class therapy for use in this condition.
On October 20, 2004, NPS Pharmaceuticals' (NASDAQ:NPSP) shares fell after presenting additional Preos data at the American College of Rheumatology.
We remain on track to achieve several key milestones this year: the announcement of topline results of the teduglutide Phase 3 study in short bowel syndrome, the continuation of our development work with PREOS and teduglutide in specialty indications, and the consolidation of our operations in New Jersey which will cut our annual facilities costs by 90 percent and increase our operating flexibility.
HP TopTools and HP OpenView DeskTop Administrator ability to use 3Com's DMI, Remote Power On, Wake-On-LAN, and PreOS NIC features will give customers a broad new range of management options that will increase MIS efficiency and reduce Total Cost of Ownership of their desktop PCs.