Compared with pEGS-N1 transfected cells, the relative expression levels of PRLR
, JAK2, STAT5 and DGAT1 in cells treated with pEGS/2SS-tPA or pEGS/2SS were dramaticlly decreased, suggesting overexpression of SS fusion gene are able to decline the expression of PRLR
, JAK2, STAT5 and DGAT1 genes.
For that, we examined ovarian PRLR
expression as well as that of several P4 production-modulating molecules and we found a consistent expression pattern along gestation for ovarian PRLR/LHR/3[beta]-HSD that contrasts with that of 20[alpha]-HSD, pinpointing PRL and LH as central players in the modulation of luteal steroidogenesis and P4 production in pregnant vizcachas.
Single-nucleotide polymorphisms g.151435C >T and g.173057T>C in PRLR
gene regulated by bta-miR-302a are associated with litter size in goats.
Restored signaling also plays an important role in the effect of SXSM due to the restored MBIP, PPIC, PRKCZ, vasoactive intestinal peptide receptor (VIPR), PRLR
In a crossbred population, prolactin receptor (PRLR
), melanocortin-4 receptor (MC4R), and leptin (LEP) polymorphisms were determined to analyse genotype effects on important production traits such as backfat thickness, loin width and average daily gain.
Because newborn G3 [CSAD.sup.-/-] often lacked milk spots, which are a predictor of survival in newborn mice, we examined the gene expression of Ltf and Prlr
which were markedly reduced in microarray analysis (Table 5).
La concentracion de PRLr
y en particular, de su mRNA, es potenciada por su propio ligando, la PRL, mediante un mecanismo autocrino/paracrino de regulacion a la alta.
Los primers para PRLR
fueron los siguientes: F 5'CCC AAA ACA GCA GGA GAA CG 3' y R 5'GGC AAG TGG TTG AAA ATG GA 3' y para ESR los primer utilizados fueron: F 5'CCT GTT TTT ACA GTG ACT TTT ACA GAG 3' y R 5'CAC TTC GAG GGT CAG TCC AAT TAG 3'.
Candidate genes were studied for litter size in 300 sows Yorkshire-Landrace; ESR, PRLR
, RBP4 y FUT1.
Antibodies Used in the Study(*) Antibody Clonality Source ER (1D5) Monoclonal Dako Ltd, Cambridge, United Kingdom PgR (1A6) Monoclonal Novocastra, Newcastle-upon-Tyne, United Kingdom PrlR
(B6.2) Monoclonal B.
DGAT1, GH, GHR, PRL and PRLR
polymorphism in water buffalo (Bubalus bubalis).
In contrast, the prolactin receptor (Prlr
, 40% of control) and the epidermal growth factor receptor (Egfr, 40% of control) were decreased as a result of in utero exposure to inorganic arsenic.