PSGL1P-Selectin Glycoprotein Ligand-1
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Similarly, PSGL1 copy number was considered as a biomarker to differentiate different types of AML [140].
Adhesion molecules involved in the recruitment of leukocytes include L-selectin, P-selectin, and E-selectin, which interact with P-selectin glycoprotein ligand 1 (PSGL1), as well as other glycosylated ligands, for example, intercellular adhesion molecule 1 (ICAM1) and vascular cell-adhesion molecule 1 (VCAM1) [6].
Nasal polyp tissues showed higher gene expression levels of the adhesion molecules P-selectin (1.62-fold, n = 7), PSGL1 (1.74-fold, n = 7), and VCAM1 (2.16-fold, n = 7) compared to associated inferior turbinates (Figure 1(a)).
Expression levels of PSGL1, ICAM1, and VCAM1 did not significantly differ between nasal polyps and inferior turbinates (Figure 1).