PUNLMPPapillary Urothelial Neoplasm of Low Malignant Potential
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All cases of PUNLMP showed negative p53 reactivity and CK20 positive in upper one third epithelium including umbrella cells.
Distribution of Patients With Urothelial Tumors by Patient Age and Tumor Type Age, (a) y PUNLMP, LGPUC, HGPUC, INVUC, Total, No.
Two (100%) of the patients with PUNLMPs who had follow-up data available were alive with no evidence of disease after 13 and 37 months.
We plan on following the 3 young children primarily with ultrasound, but will do one surveillance cystoscopy 1-year post-resection for the 2 teenagers with the PUNLMP.
9] PUNLMPs accounted for most bladder malignancies in a recent SEER review.
PUNLMP has minimal cytologicatypia and has very little invasive or metastatic potential but recurrence is seen after resection.
Differential Diagnosis of Nephrogenic Adenoma Nephrogenic Adenoma Differential Diagnosis Surface lesions (papillary) Urothelial papilloma PUNLMP Low-grade papillary urothelial carcinoma Involving deep lamina propria Prostatic adenocarcinoma and/or superficial muscle Urothelial carcinoma with bland histology Hobnail cells, solid growth of Clear cell adenocarcinoma of clear cells urinary bladder (rare) Abbreviation: PUNLMP, papillary urothelial neoplasm of low malignant potential.