Persaud explains that the difference in PUQE
score between the drug and the placebo groups was expected to be 3 points - a far cry from the difference reported in the clinical trial.
Initially, health records of pregnant women were studied and in case of primary qualifications for inclusion, they were asked to answer the PUQE questionnaire to determine the basic severity of NVP.
with the difference that researchers used Visual Scale to evaluate the severity of nausea and also counted the number of patients vomiting at various stages of the research (25), while validated PUQE questionnaire was used for this purpose in our research.
We rated the severity of NVP with PUQE questionnaire that is a reliable and standard tool for assessing these symptoms and that was one of the strengths of our study, while Rhodes scale was used for this purpose in this study.
Validation studies of the pregnancy unique-quantification of emesis (PUQE) scores.
Upon examination of a subcategory of PUQE, fingertip blood ketone levels in patients with PINV were statistically significant; statistical data are presented in Table 4.
PUQE was the scoring system for PINV severity with three classifications: low (<6), moderate ([less than or equal to]7 [less than or equal to]12), and high ([less than or equal to]13) (9).
Validity of a modified Pregnancy Unique Quantification of Emesis and Nausea (PUQE) scoring index to assess severity of nausea and vomiting of pregnancy.
Relationship between fingertip blood ketone with PUQE subgroups PUQE score (n) 1, (6) 2, (73) 3, (23) p Capillary 0.0 (0.0-0.1) 0.1 (0.0-0.32) 0.8 (0.20-1) 0.000212 blood ketone, median (IQR)
(3) the highest PUQE score for each patient during the first 3 weeks of NVP;
(4) the area under the PUQE-time curve during the first 12 weeks of gestation; later on, PUQE measures were not as commonly done to allow rigorous calculation of AUC.
The area under the PUQE-time curve was calculated by the trapezoid rule using the patients' reported PUQE scores.