Kemppainen et al., "Pancreatic secretory trypsin inhibitor
(SPINK1) gene mutations in patients with acute pancreatitis," Pancreas, vol.
Tumor-associated trypsin inhibitor (TATI),  originally identified in urine from patients with ovarian cancer, was later shown to be identical to pancreatic secretory trypsin inhibitor (PSTI).
A radioimmunoassay for measurement of human pancreatic secretory trypsin inhibitor in different body fluids.
The ingredient called pancreatic secretory trypsin inhibitor
, or PSTI, is found at its highest levels in colostrum - the milk produced in the first few days after birth.
Pancreatic secretory trypsin inhibitor, lactoferrin, and carbonic anhydrase II could be candidates for target antigens in AIP, because they are demonstrated in the commonly involved organs, such as the pancreas, biliary tree, salivary glands, gastrointestinal tract, and distal renal tubules.
Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis.
It has the ability to digest trypsin inhibitors, a property that raises the possibility that it may contribute to the pathogenesis of pancreatitis by reducing the protective concentrations of pancreatic secretory trypsin inhibitor
. The other interesting property of trypsinogen-3 is its resistance to trypsin inhibitors (12).
A similar protease inhibitor was later identified in human pancreatic juice and called "pancreatic secretory trypsin inhibitor
." By means of immunologic techniques, SPINK1 was later identified as a tumor-associated peptide and isolated from the urine of a patient with ovarian cancer.
Contribution of the CFTR gene, the pancreatic secretory trypsin inhibitor
gene (SPINK1) and the cationic trypsinogen gene (PRSS1) to the etiology of recurrent pancreatitis.
Pancreatic Secretory trypsin inhibitor (PSTI) (4) also known as serine protease inhibitor Kazal type 1 (SPINK1), is a potent low-molecular-weight inhibitor of trypsin synthesized in the acinar cells of the pancreas, where it may be essential for inactivation of inappropriately activated trypsin (1, 2).
The primary structure of the human pancreatic secretory trypsin inhibitor. Amino acid sequence of the reduced S-aminoethylated protein.
TATI is identical to the earlier described pancreatic secretory trypsin inhibitor
(PSTI) (2), which also is called the Kazal inhibitor (3).