Peroxisome proliferator activated receptors
and their ligands: nutritional and clinical implications-a review.
Telmisartan, an angiotensin type 1 (ATI) receptor blocker, reportedly has beneficial effects on glycemic control more than other ATI receptor blockers and this unique feature of telmisartan can be due to its peroxisome proliferator activated receptors
(PPARg) agonistic activity3.
CP, cyclophosphamide; GCEE, gamma-glutamylcysteine ethyl ester; PPAR[gamma], peroxisome proliferator activated receptor
Peroxisome Proliferator Activated Receptors
(PPARs) are ligand-activated transcription factors belong to nuclear hormone recep tor superfamily.
Expression of peroxisome proliferator activated receptor
mRNA in normal and tumorigenic rodent mammary glands.
cDNA cloning, chromosomal mapping, and functional characterization of the human peroxisome proliferator activated receptor
A Gly482Ser missense mutation in the peroxisome proliferator activated receptor
[gamma] coactivator-1 is associated with altered lipid oxidation and early insulin secretion in Pima Indians.
and Mitsubishi Pharma Corporation today announced a licensing agreement for the late-stage development and commercialization of MCC-555 (a peroxisome proliferator activated receptor
(PPAR) agonist) for the treatment of diabetes and other metabolic disorders.
Adipogenic peroxisome proliferator activated receptor
gamma (PPARG), which is a nuclear receptor and transcription factor, regulates lipid metabolism by controlling the expression of various lipogenic genes, such as adipocyte fatty acid binding protein 4 (FABP4), lipoprotein lipase, acyl-CoA synthase, and fatty acid transport protein (Sarjeant and Stephens, 2012).
Prolonged dietary treatment with conjugated linoleic acid stimulates porcine muscle peroxisome proliferator activated receptor
gamma and glutamine-fructose aminotransferase gene expression in vivo.
Most of the pleiotropic effects of peroxisome proliferators are mediated by the peroxisome proliferator activated receptor
(PPAR), a ligand-activated transcription factor that is expressed at lower levels in humans than in rats and mice.
DRF4158 is a Peroxisome Proliferator Activated Receptor
(PPAR) alpha gamma agonist or a dual-acting insulin sensitizer that was out-licensed to Novartis in May 2001.