PhNRPhotopic Negative Response
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The waveform of the short-flash ERG in the fellow eye shows a deep negative wave following the b-wave, which was designated as PhNR [Figure 1]a.
For both flash durations, no statistical differences were found in the mean IT of the a-wave ( P = 0.76), b-wave ( P = 0.16), and PhNR ( P = 1.00) in response to the short-flash and a-wave ( P = 0.78), b-wave ( P = 0.15), d-wave( P = 0.29), and i-wave ( P = 0.25) in response to the long-flash between the lasered eyes and fellow eyes [Table 2].
As expected, no significant differences were found statistically in mean amplitude between the two eyes in the a-wave ( P = 0.29), b-wave ( P = 0.61), and PhNR ( P = 0.96) in response to the short flash or in the a-wave ( P = 0.88), b-wave ( P = 0.99), d-wave ( P = 0.80), and i-wave ( P = 0.10) in response to long flash.
An example of this is the PhNR, which is thought to reflect ganglion cell activity.
We found that TA- and BBG-assisted ILM peeling resulted in less decrease in the PhNR amplitude than after ICG-assisted vitrectomy.
Although ICG was not associated with a significant decrease in the RNFL thickness compared to BBG or TA, we found that the RGC component of the electroretinogram, the PhNR, was significantly reduced after MH surgery [23].