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Merkel cells) Absent Present AR (tumor cells) + - Abbreviations: PHLDA1, pleckstrin homology-like domain, family A, member 1 protein; AR, androgen receptor.
Among the topics are inositol lipids and RTPC channel activation, pleckstrin homology domains and phospho-inositides, inositol polyphosphate kinases as regulators of nuclear function, and the evolution of the diverse biological roles of inositols.
This amino acid substitution occurs within the pleckstrin homology domain in the amino-terminal region of the protein and is presumed to alter normal B-cell signaling by disrupting protein-protein interactions.
Especially, 581 genes that have Hanwoo-specific SNPs at least five are associated with immune activation by external stimuli, through epidermal growth factor-like domain (EGF-like domain), pleckstrin homology domain (PH domain), immunoglobulin subtype 2, and thrombospondin (Figure 3) (Chen et al.
The protein structure of PLD4 is also different from PLD1 and PLD2, since PLD4 is a glycoprotein with a single transmembrane domain and does not contain Phox homology (PX) or pleckstrin homology (PH) domains, both of which are involved in membrane targeting and activation of PLD.
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH).
A new heterozygous mutation (R714C) of the osteopetrosis gene, pleckstrin homolog domain containing family M (with run domain) member 1 (PLEKHM1), impairs vesicular acidification and increases TRACP secretion in osteoclasts.
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.
25 calsenilin PSCD1 pleckstrin homology, Sec7 and coiled-coil -0.
In addition, alternative splicing forms of cytoplasmic dynein 1 (DYNCl), AXL receptor tyrosine kinase (AXL), pleckstrin homology domain containing, family G (with RhoGef Domain) member 1 (PLEKHG1), and the cordon-bleu WH2 repeat protein-like 1 (COBLL1) showed reversed expression patterns before and after exercise in skeletal muscle (Park et al.
2011) recently found thac down-regulation of protein phosphatase 2A and pleckstrin homology domain leucine-rich repeat protein phosphatase 2 contribute to Akt activation in arsenite-treated mouse epidermal JB6 CI41 cells.
Defects of the signaling pathways, including G protein activation, phospholipase C activation, calcium mobilization, pleckstrin phosphorylation, and tyrosine phosphorylation, have also been described.
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- plebis dux
- Plecia nearctica
- Pleckstrin homology
- Pleckstrin Homology and Tec Homology
- Pleckstrin homology domain
- pleckstrin homology domain interacting protein
- pleckstrin homology, Sec7 and coiled-coil domains 1
- pleckstrin homology, Sec7 and coiled-coil domains 2
- pleckstrin homology, Sec7 and coiled-coil domains 21 PSCD2
- pleckstrin homology, Sec7 and coiled-coil domains 3
- pleckstrin homology, Sec7 and coiled-coil domains 4, cytohesin-4
- pleckstrin homology, Sec7 and coiled/coil domains 2
- pleckstrin homology, Sec7 and coiled/coil domains 3
- pleckstrin homology, Sec7 and coiled/coil domains 4
- Plecnik, Jože
- Plecnik, Joze
- Plecoglossus altivelis