Active peptic ulcer disease in patients with hepatitis C virus-related cirrhosis: the role of Helicobacter pylori infection and portal hypertensive gastropathy
. Can J Gastroenterol.
Preatoni et al., "Natural history of portal hypertensive gastropathy
in patients with liver cirrhosis.
Portal Hypertensive Gastropathy
, n (%) 135/173 (78.03)
Development and progression of portal hypertensive gastropathy
in patients with chronic hepatitis C.
In this group 38 bleeding episodes were from varices and 10 from non-variceal sources including duodenal ulcer (N=1), portal hypertensive gastropathy
(N=2), Mallory-Weiss tear (N=1) and oesophageal ulceration (N=2), with 4 sites not identified with certainty during endoscopy.
PHG is a common manifestation of portal hypertension, and therefore, we aimed at finding out if blood ammonia levels correlate with the presence and severity of portal hypertensive gastropathy
in cirrhotic patients.
It is therefore pertinent to have gastric endoscopy in patients with PVT as portal hypertensive gastropathy
is more often present in the acute PVT, secondary to cancer or cirrhosis, whereas large esophageal varices are often present in patients with chronic PVT.
effect of band ligation on portal hypertensive gastropathy
and development of fundal varices.
Upper GI endoscopy and colonoscopy were performed independently, and the presence or absence of esophageal varices (EV), gastric varices (GV), portal hypertensive gastropathy
(PHG), and portal hypertensive colonopathy (PHC) was determined.
The importance of this syndrome is characterized by the frequency and severity of complications, such as massive upper GI bleeding from ruptured gastroeso-phageal varices and portal hypertensive gastropathy
, ascites, hepatorenal syndrome and hepatic encephalopathy.
It is often confused with portal hypertensive gastropathy
, both of which can occur in patients with cirrhosis [4,5].
* Portal hypertensive gastropathy
is seen in patients with portal hypertension who may present with gastric haemorrhage due to dilatation, congestion and proliferation of mucosal blood vessels, most prominent in the proximal stomach.