Engel et al (1989)  compared inhaled budesonide delivered via pressurized metered dose inhaler and turbuhaler and found no statistically significant differences in FVC.
Comparative study of budesonide as a nebulized suspension vs pressurized metered dose inhaler in adult asthamatics.
One hundred patients were enrolled, based on the following inclusion and exclusion criteria; Male patients between the age of 15-60 year, having asthma or COPD using pressurized metered dose inhalers
on regular basis were included in the study.
Mitchell, et al., "The Abbreviated Impactor Measurement (AIM) Concept: Part 2--Influence of Evaporation of a Volatile Component--Evaluation with a 'Droplet Producing' Pressurized Metered Dose Inhaler
(pMDI)-Based Formulation Containing Ethanol as Co-Solvent," AAPS Pharm.
Comparison of the aerosol velocity and spray duration of Respimat Soft Mist inhaler and pressurized metered dose inhalers
. J Aerosol Med.
In vitro properties of pressurized metered dose inhalers
with and without spacer devices.
Leveraging its 45 person sales force, FSC markets three pediatric pharmaceutical products indicated for infection, allergy, gastroesophageal disease, and a medical device for the administration of aerosolized medication using pressurized Metered Dose Inhalers
(pMDIs) for the treatment of asthma.
The device is intended to be used by these patients to administer aerosolized medication from most pressurized Metered Dose Inhalers
. The intended environments for use include the home, hospitals and clinics.
* Landmark, an award-winning integrated dose indicator for pressurized metered dose inhalers
(pMDIs), has been developed in compliance with FDA guidance to integrate a dose-counting mechanism into pMDI drug products.
* Inhaled drug delivery - dry powder inhalers (DPIs) and pressurized metered dose inhalers
3M also introduced two new designs for inhalation drug delivery with pressurized metered dose inhalers
(pMDIs), 3M Plasma Coating Technology and the 3M Face Seal Valve.