Imipenem-cilastatin (1 g q6h) and ceftazidime (2g q8h
) combined with tigecycline (100 mg q12h) were started.
He was started on vancomycin (15 mg/kg IV q8h
) and ceftriaxone (50 mg/kg IV q12h) empirically.
Dosing can be scheduled q12h or q24h 11-52 (candidiasis) 200 mg PO q12h 80-100 (aspergillosis) 6-27 (candidiasis) 200-600 mg PO 20 (aspergillosis) q24h 34 Loading dose 372 mg q8h
x 6 doses, then 372 mg IV q24h 1 (or 10-20) Loading dose Echinocandins 200 mg IV, then 100 mg IV q24h 1 (or 7.5-30) 150 mg IV q24h 1 (or 10-20) Loading dose 70 mg IV, then 50 mg IV q24h Antifungal class TDM goal References (trough con- centrations in mg/L)  Not 18, 27 recommended Not 25 recommended Not 25 recommended Not 25 recommended 0.5-1 (measured 54 during the first Triazoles 5 days of therapy and regularly after) Not used.
Patients in the 750-mg/ 1,500-mg q12h and 1,000-mg/2,000-mg q8h
groups met the primary efficacy endpoint of an 80% or greater clinical success (83% and 92%, respectively) within 2-3 days.
Because of its administration (q8h
frequency), its parenteral cost is somewhat lower than that of ampicillin.
As a result, patient was started on levetiracetam 500 milligrams intravenous q12h and phenytoin 100 milligrams intravenous q8h
and placed on a video electroencephalogram (vEEG).
The patients were treated with Streptomycin 30 mg/kg/day IM in two divided doses for 10 days, or some were given Gentamicin 2.0 mg/kg IV loading dose and then followed up with 1.7 mg/kg q8h
Table 1: Primary Prophylaxis For Toxoplasmosis In Aids Patients (37) For the toxoplasma-seropositve HIV-infected individuals Suggested regimen TMP/SMX One double-strength tablet daily Alternative regimens Pyrimethamine--Dapsone Pyrimethamine, 50mg once each week, plus dapsone, 50mg qd, plus folinic acid (leucovorin), 25mg qd Pyrimethamine, 75mg once each week, plus dapsone, 200 mg once each week, plus folinic acid (leucovorin), 25 mg qd TMP/SMX One single-strength tablet daily For the Toxoplasma-seropositive HIV-infected pregnant women Spiramycin 1 g q8h
Table 2 Age in years Number of patients % 20-30 10 33.3 31-40 12 40.0 41-50 6 20.0 51-60 2 6.7 Total 30 100.0 Table 3: Male: Female ratio was 2.01.
An IV was started of normal saline solution 0.9%, 1000 ml q8h
, and antibiotics were initiated to include Rocephin (ceftriaxone) of 2 g q12h and Flagyl (metronidazole) of 500 mg q6h.
After abortion, her general condition worsened, respiratory distress developed, and the treatment was switched to meropenem (1 g, q8h
) and levofloxacin (750 mg, q24h).
Topical rimexolone 1% q6h, cyclopentholate q8h
, and ciprofloxacin 500mg q12 PO were prescribed with a bandage contact lens to the left eye.