QCDL - What does QCDL stand for? The Free Dictionary
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QCDL model Change in Mean QTc p-Value Pollutant Modifier [msec (95% CI)] p-Value interaction BC High GSS 3.85(0.78 to 6.93) 0.01 0.57 Low GSS -0.56(-3.90 to 2.78) 0.74 [NO.sub.2] High GSS 3.50(-1.86 to 8.87) 0.20 < 0.01 Low GSS 0.29(-4.56 to 5.14) 0.90 CO High GSS 6.52(0.49 to 12.55) 0.03 0.08 Low GSS 3.94(-1.28 to 9.15) 0.14 GSS measures the genetic susceptibility of a participant to oxidative stress by adding all the unfavorable genotypes of the participant.
Our observation of effect modification by diabetic status in the associations between the cumulative effect and 4 hr before ECG measurement lag effect of BC and [NO.sub.2] exposure and prolonged QTc for the QCDL and hourly lag models may be due to a higher likelihood of persons with diabetes to have prolonged QTc than those without diabetes.
Our QCDL model estimates showed significant QTc prolongation in association with increasing BC and CO in 50% of the study population with higher genetic susceptibility to oxidative stress (as measured by GSS).