QSAR

(redirected from Quantitative structure-activity relationship)
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AcronymDefinition
QSARQuantitative Structure-Activity Relationship
QSARQuality System Assessment Recognition (International Organization for Standardization)
QSARQuality Service Activity Report
QSARQuébec Secours Search and Rescue (Canada)
QSARQuality System Audit Report
References in periodicals archive ?
Summary: Quantitative structure-activity relationships were constructed for 107 inhibitors of HIV-1 reverse transcriptase that are derivatives of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Dearden, "The history and development of quantitative structure-activity relationships (QSARs)," International Journal of Quantitative Structure-Property Relationships, vol.
Tropsha, "Use of cell viability assay date improves the prediction accuracy of conventional quantitative structure-activity relationships models of animal carcinogenicity," Environmental Health Perspectives, vol.
Lakhlifi, "Quantitative structure-activity relationship studies of dibenzo[a,d]cycloalkenimine derivatives for non-competitive antagonists of N-methyl-d-aspartate based on density functional theory with electronic and topological descriptors," Journal of Taibah Universityfor Science, vol.
OBJECTIVES: We investigated the interactions between HO-PBDEs and TR[beta] to identify critical structural features and physicochemical properties of HO-PBDEs related to their hormone activity, and to develop quantitative structure-activity relationship (QSAR) models for the thyroid hormone activity of HO-PBDEs.
Quantitative structure-activity relationship analysis of pyridinone HIV-1 reverse transcriptase inhibitors using the k nearest neighbor method and QSAR-based database mining.
Quantitative structure-activity relationship (QSAR) methods have been widely applied in drug discovery, lead optimization, toxicity prediction, and regulatory decisions.
A quantitative structure-activity relationship (QSAR) for a Draize eye irritation database.
Quantitative structure-activity relationship (QSAR) models and qualitative SAR approaches have had some success in identifying and depicting structural features that contribute to the ability of a chemical to interact with steroid hormones, for both the estrogen receptor (ER) (Anstead et al.
Quantitative structure-activity relationship work on the structural features of estrogen receptor ligands shows that an unhindered hydroxyl group on an aryl ring and a hydrophobic group attached para to the hydroxyl group are essential (Anstead et al.
Perspectives on three-dimensional quantitative structure-activity relationship (3D-QSAR)/comparative molecular field analysis (CoMFA) in determining estrogenic effects.
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