RAG2

AcronymDefinition
RAG2Recombination-Activating Gene 2
References in periodicals archive ?
In PI 243540 (Rag2) and the susceptible genotype 'Wyandot,' it was observed that aphids had fewer prolonged phases of active salivation (El), pathway events, and non-probing intervals, and that fewer insects reached the phloem on PI 243540 (Todd et al.
In our study, we observed less severe colitis in Rag2 k.o.
RAG2 has been shown to specifically recognise the histone modification H3K4me3, a marker enriched at active promoters, via its PHD finger, an interaction which also stimulates RAG complex activity [65, 66].
The new taxon is probably a relatively recently evolved species as evidenced by the lack of lineage sorting in the nDNA locus (as RAG2 is known to evolve relatively slowly, Sullivan et al.
La segunda es una respuesta con un grado muy fino de especificidad, en la cual se distinguen dos caracteristicas sobresalientes: 1-requiere de la presentacion antigenica, que es llevada a cabo por las celulas presentadoras de antigeno (CPA) en el contexto de moleculas del complejo mayor de histocompatibilidad (CMH) y 2-los sistemas de reconocimiento especifico se basan en receptores moleculares los cuales generan su repertorio de posibilidades usando un sistema de recombinacion a traves de las enzimas recombinasas RAG1 y RAG2 (Cooper et al.
RAG1 y RAG2, y sintetizan endonucleasas de secuencia especifica que activan las reorganizaciones V (D) J.
Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency.
The gene shuffling that produces B cell variations is guided by proteins encoded by recombinase activating genes, RAG1 and RAG2. Researchers have believed that the shuffling ceases once the mature B cells leave the marrow.
Based on motif analysis of PAX5, we searched out 28 PAX5 target genes, that is, BAX, BCL2, BLK, CCND1, CD19, D79A, CDKN1A, FCER2, FHL2, LEF1, MET, MMP1, MYCNA, PRDM1, PRKCE, RAG2, RB1, TIMP1, TP53, XBP1, EGR1, ESR1, ELK1, ETS1, KCNH4, VPREB1, IGLL1, and KCNH8.
glycines that colonized soybean plants with Raglc, Rag2, Rag3, and Rag4 genes as biotype 3.
La importancia de los linfocitos en el establecimiento de la placa aterosclerotica se ha determinado gracias a experimentaciones en modelos animales producto del cruce entre especimenes con deficiencia en la produccion de apolipoproteina E (apoE -/-) o del receptor de LDL (LDLr -/-) y ratones con deleccion en el gen RAG2, indispensable para el desarrollo de linfocitos T y B, y en algunas investigaciones el cruce se realizo con ratones con inmunodeficiencia combinada severa.
These recombination-activating genes, known as RAG1 and RAG2, sit right next to each other, suggesting they were once packaged together as a transposase, says Schatz.