RARB

AcronymDefinition
RARBRear Anti Roll Bar (automotive product)
RARBRetinoic Acid Receptor Beta (genes)
RARBRisk Assessment and Review Board
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References in periodicals archive ?
Another study of 23 primary UMs examined CpG promoter methylation of several cancer-related genes including p16INK4a , Tissue inhibitor of metalloproteinases 3 ( TIMP3 ), RASSF1 , RARB , FHIT , hTERT , and APC .
Combining parallel testing of PAX1, DAPK1, RARB, WIF1, and SLIT2 DNA methylation and HPV DNA increases specificity to identify cervical cancer and achieves better precision than single HPV DNA testing does [74-76].
(23) MGMT ve DAPK1: %38 metile RARB RARB: %31.2 metile Zhao ve Osteogenez COL1A1 ve Mutasyon COL1A1: 74/200 (37) ark.
Jarmalaite, "Frequent methylation of RASSF1 and RARB in urine sediments from patients with early stage prostate cancer," Medicina (Kaunas, Lithuania), vol.
Finally we also analyzed the genes for retinoid receptors RARB and RXRG, which were found to be methylated in many types of cancer [28].
These candidate genes include DAPK (death-associated protein kinase 1), CDH1 [cadherin 1, type 1, E-cadherin (epithelial)], RASSF1 [Ras association (RalGDS/AF-6) domain family member 1], CDKN2A (cyclin-dependent kinase inhibitor 2A), FHIT (fragile histidine triad), MGMT (O6-methylguanine-DNA methyltransferase), and RARB (retinoic acid receptor, beta).
This change was accompanied by alterations in the levels of several other molecules, including increases in RARb and peroxisome proliferator--activated receptor (PPAR) C coactivator 1a (PGC1[alpha]) expression and a decrease in PPAR[gamma] expression.
(19) See M(K), ibid at 29-31; RARB v British Columbia, 2001 BCSC 667 at para 141 (available on CanLII)[RARB], See also Ipp Committee, Review of the Law of Negligence: Final Report (2002) at 85-86, online: Review of the Law of Negligence <http://revofneg.treasury.gov.au/content/review2.asp> [Ipp Report]; Graeme Mew, The Law of Limitations, 2nd ed (Markham: Butterworths, 2004) at 12-13; Kent Roach, "Reforming Statutes of Limitations" (2001) 50 UNBLJ 25; Richard W Bauman, "The Discoverability Principle: A Time Bomb in Alberta Limitations Law" (1993) 1 Health LJ 65 at 67-68.
Methods: The methylated promoter regions of cancer-related genes cadherin 1 (CDH1) and retinoic acid receptor beta (RARB) served as target DNA sequences.
For example, Achille and collaborators investigated global DNA methylation and gene expression of CDKN2A (cyclin-dependent kinase inhibitor 2A), CDKN2B (cyclin-dependent kinase inhibitor 2B), both regulators of the cell cycle at the G1 checkpoint; HIC1 (transcriptional repressor 1), a growth regulatory molecule that acts as a tumor repressor; RARB (retinoic acid receptor beta), a retinoic acid nuclear receptor which also mediates cellular signalling, growth, and differentiation; CDH1; and APAF1 (apoptotic peptidase activating factor 1), an apoptosis initiator by cleavage of caspase 9, before and during hypomethylating therapy, with the purpose of observing whether early changes could predict clinical response.
(48,49) Other tumor suppressor genes frequently hypermethylated in OPSCC and other smoking-related cancers include RARb, (50-53) RASSFI, (44,54,55) MGMT, (10,47,50,56,57) and GATA4.