RDBPCRandomized, Double-Blind, Placebo-Controlled
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Use of RDBPC studies could not be applied to test the holistic model, as it is individualized and employing multiple treatment modalities at any given time.
Besides, the middle circle represents the gold standard for the analysis, defined by the pooled combined symptom and medication score from patients of a randomized, double-blind, and placebo-controlled (RDBPC) clinical study.
Abbreviations AR: Allergic rhinitis CCF: Cross-correlation coefficient CSMS: Combined symptom medication score HE: Hesse NRW: North Rhine-Westphalia RDBPC: Randomized, double-blind, placebo-controlled RRTSS: Retrospective rhinoconjunctivitis total symptom score RTSS: Rhinoconjunctivitis total symptom score TRMS: Total rescue medication score.