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Ovarian sensitivity index (OSI) was calculated by dividing the total administered rFSH dose by the number of oocytes retrieved at OPU to obtain the FSH-to-retrieved oocyte ratio (10).
One hundred non-PCOS patients aged under 40 years and with basal FSH < 10mUI/ml undergoing ovarian stimulation are randomly divided into two groups: Group A treated with 400 jWg of folic acid for the 3 months before and during rFSH administration and Group B treated with a daily dose of 4000 mg of myoinositol into two administrations/day in addition to 400 ,wg of folic acid for the 3 months before and during rFSH administration.
Conclusion: Our data revealed no statistically significant differences in the mean oocyte number, embryo quality, clinical pregnancy rate, or live birth rate between the hMG, hFSH, rFSH, and sequential hFSH/rFSH protocols.
On the opposite, sperm motility was only positively significantly correlated to live-birth in the 2 rFSH groups.
The European Commission approval of the product is based on a comprehensive clinical data package, including results from the Phase 3 ESTHER trials (Evidence-based Stimulation Trial with Human rFSH in Europe and Rest of World).
(2013) (150 mg/dan, 5 dana) B: M + rFSH3 (75 IU) C: rFSH (75 IU) Abd A: M (1700 mg/day) + L Elgafor 146 (5 mg/day, 5 days), (2013) B: LOD/A: M (1700 mg/dan) + L (5 mg/dan, 5 dana), B: LOD Morin A: M obese 1500 mg/day; Papunen normal body mass - 1000 mg/day) et al.
Regarding stimulation, significant differences were found between the GnRH-antagonist and GnRH-agonist groups in total rFSH dose (mean 1,522 IU vs.
Induction with recombinant FSH (rFSH) was started once pituitary down regulation was confirmed, for five days (day 3 to 7).
Oocytes were cultured in 20 [micro]l droplet of global media supplemented daily with 75 mIU/mi rFSH (Sereno, Switzerland) and 10 /U/m/ hCG under mineral oil at 37[degrees]C in 5% C[O.sub.2] in air for 24 hr.
Recovery of spermatozoa after rFSH / hCG treatment, and subsequent ICSI/IVF, in a male with testicular atrophy due to sever congenital hypogonadotrophic hypogonadism.
to develop and commercialize the latter's Recombinant Follicle Stimulating Hormone (rFSH).
Co-administration of metformin during rFSH treatment in patients with clomiphene citrate-resistant polycystic ovarian syndrome: a prospective randomized trial.
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