RPFRReduced Partition Function Ratio
RPFRRenal Plasma Flow Rate
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We observed significant declines in adjusted means from the lowest to highest quartile of RPFR for the proportion of cycles resulting in successful fertilization (10% decrease, p-trend = 0.04), implantation (31%, p-trend = 0.02), clinical pregnancy (41%, p-trend = 0.004) and live birth (38%, p-trend = 0.05), adjusted for age, BMI, race/ethnicity, year of cycle, and infertility diagnosis (Figure 2, Tables 3 and 4).
Similar trends with oocyte count were not observed for DPHP, ip-PPP, or RPFR (p-trends >0.3).
These findings are clinically relevant, as the adjusted proportion of live births in the highest quartile of RPFR was 0.30 as compared to 0.48 in the lowest quartile (adjusted difference in proportions = 0.18).