RRDR

AcronymDefinition
RRDRRifampicin Resistance-Determining Region (microbiology)
RRDRResearch Resource Division for Refugees (Carleton University; Canada)
RRDRRaw Radar Data Recorder
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Mutation in the RRDR region of rpoB is detected using 8 wild type immobilized probes along with 4 other probes that detect most common substitution at codon 516, 526 and 531 as in Figure-1.7 Each probe binds to its corresponding complementary codon.
TB-SPRINT is commercial assay used for determining DNA polymorphism at the DR locus and simultaneously detects mutation in RRDR region of rpoB gene.10
Molecular Characterization and Spoligotyping Analysis of Multi Drug Resistant Mycobacterium tuberculosis from a High TB Endemic Area of Pakistan
For the detection of mutations at codon within RRDR of rpoB for rifampicin, real-time PCR-HRM analysis was performed.
Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin
Rifampicin resistance as reported in previous studies is due to mutation in the Rifampicin Resistance Determining Region (RRDR) of rpoB gene.
Molecular diagnosis of multidrug-resistant mycobacterium tuberculosis isolates in and around Mumbai
About 200 ngof DNA from culture isolates while 5 L of DNA from clinical specimens was used as target for the amplificationof hotspot region of rpoB gene by polymerase chainreactions.Amplification of RRDR of rpoB Gene Amplification of RRDR of rpoB gene of M.
Identification of single nucleotide polymorphism in rpoB gene among Mycobacterium tuberculosis isolates from Pakistan
The 365 bp region for V176F mutation and 749 bp region containing upstream region of RRDR were amplified and sequenced for mutation.
Molecular Characterization of Multidrug-Resistant Isolates of Mycobacterium tuberculosis from Patients in Punjab, Pakistan
Silent mutations within the RRDR of the rpoB gene have been reported,21 though codon 526 mutations are very strongly associated with RIF resistance.
Line probe assay for detection of rifampicin and isoniazid resistant tuberculosis in Pakistan
Shortly thereafter, a line probe assay (GenoType MTBDRplus; HAIN Lifescience, Nehren, Germany) performed by Southeastern National TB Center (Gainesville, FL, USA) on the culture of the sputum specimen obtained at admission indicated an inhA point mutation but no mutation in the RRDR region of the rpoB gene, which suggested that the isolate was INH resistant but RIF susceptible.
Discordance in Mycobacterium tuberculosis rifampin susceptibility
The samples consisted of pooled PCR products containing a 193-bp fragment from the RRDR of the rpoB gene of Mtb that were amplified from different Rmp-r strains of Mtb (minimum inhibitory concentration >2 mg/L rifampin).
Capillary electrophoresis-based heteroduplex analysis with a universal heteroduplex generator for detection of point mutations associated with rifampin resistance in tuberculosis
RRDR (1999) INSCAN -- International Settlement Canada Research Resource Division for Refugees Volume 12 (4), Carleton University RRDR, Ottawa, Canada.
"BIRDS IN A GILDED CAGE": RESETTLEMENT PROSPECTS FOR ADULT REFUGEES IN NEW ZEALAND
Amplification of RRDR of rpoB gene yielded 270 bp products compared to DNA size marker in agarose gel electrophoresis (Fig.
Detection of genomic mutations in katG, inhA and rpoB genes of Mycobacterium tuberculosis isolates using polymerase chain reaction and multiplex allele-specific polymerase chain reaction
This region is known as the rifampicin resistance-determining region (RRDR), or "hotspot," and is used as a target for direct sequencing and commercial line probe assays.
Rifampicin resistance in tuberculosis outbreak, London, England
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