This evidence supports the extension of the range of NRIV infection to goats (complete sequences already had been derived from a human and from mosquitoes ) and demonstrates the occurrence of NRIV during the 2010 RVFV
outbreak in Mauritania.
infection was confirmed in animals by the Agriculture Research Council-Onderstepoort Veterinary Institute (ARC-OVI) and the University of Pretoria.
Viruses used in production of ELISA antigenic materials were the 4 DENVs (DENV-1 Hawaii, DENV-2 New Guinea C strain [6,7], DENV-3 H87 strain, and DENV4 H241 strain ); WNV EG101 strain (9); YFV Asibi strain (IgM ELISA) or YFV 17D strain (Connaught) (IgG ELISA) (10); CHIKV Indo23574 strain; RVFV
ZH 501 strain (11); EBOV Zaire-76 strain (12); MBGV Musoke strain (13); CCHFV IbAr10200 strain (14); and LASV Josiah strain (15).
was isolated from newborn mice that were intracerebrally inoculated with a blood sample from the patient.
Human samples were tested for IgM and IgG and by reverse transcription PCR for RVFV
These cases led to identification of 2 additional confirmed cases of acute RVF (positive for IgM against RVFV
RNA) in Adrar and Inchiei Provinces.
Most infections with RVFV
in humans are asymptomatic or self-limiting, mild, influenza-like illness.
During May 9-July 30, 2010, ovine and caprine flocks showing clinical signs compatible with RVFV
infection were reported to Namibian Veterinary Service.
Apart from those observations, the RVFV
situation in Mozambique is still poorly understood.
is transmitted between ruminants mainly by bites of mosquitoes of several genera (1).
With the rapid progress of molecular biology and genetic techniques in recent years, studies of prevailing circulating variants of RVFV
have pointed to a recent common ancestor that existed during 1880-1890.
travels is unclear but probably involves movement of infected livestock or mosquitoes.