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Some patients of RVVC may benefit from once weekly fluconazole (200mg) for 8 weeks, followed by fortnightly administration for 4 months, and monthly dosage for the next 6 months ( Donders' regime).
albicans persistence in patients with RVVC was evaluated by Beikert et al.
compared standard homeopathy and monthly itraconazole for treating RVVC in a prospective study of 150 patients (25).
Studies evaluating the effectiveness of probiotics in preventing RVVC have shown conflicting results.
A vaginal culture to test for Candida may also be considered and should be obtained from patients with RVVC to confirm the clinical diagnosis and to identify unusual species (including non-Calbicans species), particularly Candida glabrata.
An estimated 5-8% of women of child-bearing age suffer from recurring episodes of acute vulvovaginal candidiasis, a syndrome termed RVVC.
There is a significant unmet medical need for a safe and effective oral therapy to treat RVVC.