Material and Methods: This randomized controlled clinical trial
was conducted on 150 patients.
For that reason, historical anemia guidelines (NKF, 1997) were based upon a preponderance of observational studies along with expert opinion and not the preferred randomized controlled clinical trial
. We now know that treatment options or clinical decisions are best based upon cause and effect analysis.
Was it a randomized controlled clinical trial
involving thousands of people?
EVIDENCE-BASED ANSWER Most recent randomized controlled clinical trials
have not found a benefit in antioxidants (vitamin C, vitamin E, and/or beta-carotene) for preventing cardiovascular disease, including stroke.
And just this past December a randomized controlled clinical trial
of acupuncture for a group of 104 women with breast cancer undergoing a highly emetogenic chemotherapy regimen found that those who were given acupuncture along with standard antiemetic pharmacotherapy experienced significantly fewer episodes of nausea during a 5-day study period (JAMA 284:2755-61, 2000).
A randomized controlled clinical trial
which recruited 207 interventional cardiology procedure patients was carried out in four International Cardiology Centres across US and Europe.
The researchers investigated the independent and combined effects of diet-induced weight loss and regular exercise in a one-year randomized controlled clinical trial
, funded by the National Institute on Aging.
That gender effect was not seen in another large randomized controlled clinical trial
comparing fenofibrate to placebo, so "the clinical significance of this subgroup finding is unclear," the FDA noted.
Although this novel finding is "encouraging" and a confirmatory large randomized controlled clinical trial
is likely, the study results were only partly positive; after all, the hypothesis was that stimulating the mineralocorticoid receptor would also boost the overall response rate--and it didn't happen, Dr.
Use of ultramolecular potencies of allergen to treat asthmatic people allergic to house dust mite: Double blind randomized controlled clinical trial
. BMJ 2002; 324:520-3.
The DSMB noted that more than 320 patients have already been recruited and recommended that Athenex continue this study and complete the recruitment of patients.The Oraxol 001 Phase III clinical trial is a randomized controlled clinical trial
comparing Oraxol monotherapy against intravenous, or IV, paclitaxel monotherapy in patients with metastatic breast cancer.
Recently, study results were published from an impressive randomized controlled clinical trial
assessing the effectiveness of telephone call counseling to improve osteoporosis medication adherence (Arch.