Uysalol et al (17) reported that serum Cu, Cu/Zn ratio was significantly higher and vitamin D and Zn levels were significantly lower in patients with recurrent wheezing
. El-Kholy et al (8) assessed serum Zn and Cu levels in atopic dermatitis patients, bronchial asthma and healthy controls and found that Zn levels were lower and Cu levels were higher than control group.
Primary care providers (PCPs) are often asked how the disease will progress, or which children will "develop true asthma" versus "outgrow asthma." The asthma predictive index (API; https://www.mdcalc.com/asthma-predictive-index-api) is a tool that uses simple, clinically based parameters to predict the likelihood that young children with recurrent wheezing
will develop persistent asthma later in school age.
The researchers found that 31.1 and 41.8 percent of the infants in the sustained supplementation and diet-limited supplementation groups, respectively, had recurrent wheezing
by 12 months' adjusted age (difference, −10.7 percent; 95 percent confidence interval, −27.4 to −2.9 percent; relative risk, 0.66; 95 percent confidence interval, 0.47 to 0.94).
To include only children at risk of having asthma, the inclusion criteria were as follows: outpatients attending the respiratory center of the hospital with an age 6 to 20 months; recurrent wheezing
, defined as three or more previous episodes of wheezing with clinical improvement after bronchodilators (assessed by a physician), together with a familial history of asthma or any other clinical finding indicating atopy (e.g., allergic rhinitis or eczema) in one or both parents and or a personal history of allergic dermatitis.
He was diagnosed as asthma because of a history of recurrent wheezing
episodes and airway hyperresponsiveness suggested by lung function test.
The incidence of asthma and recurrent wheezing
in their children at age 3 years was lower by 6.1%, but this did not meet statistical significance; however, the study may have been underpowered.
Children with recurrent wheezing
who have eczema or allergies may respond well to regular inhaled corticosteroid (ICS) treatment (SIGN, 2012).
In older children, school-age and up, the most common--by far --cause of recurrent wheezing
Common findings include recurrent wheezing
, coughing, trouble breathing, and chest tightness.
Slightly more than half (51.2%) had a positive specific IgE, 24.5% had a positive skin prick test, 22.7% had atopic dermatitis, and 15.6% had recurrent wheezing
A clinical index to define risk of asthma in young children with recurrent wheezing
. American Journal of Respiratory Critical Care Medicine, 162(4), 1403-1406.
The relationship of RSV-specific immunoglobulin E antibody responses in infancy, recurrent wheezing
, and pulmonary function at age 7-8 years.