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RyR3Ryanodine Receptor Type 3
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Additionally, RYR3 is expressed at low levels by skeletal muscle cells (36), and it is much more sensitive to activation by caffeine compared with RYR1 (36).
5) Nonstandard abbreviations: RyR1, RyR2, and RyR3, ryanodine receptor type 1, 2, and 3; FKBP12.
To verify that ryanodine pretreatment in fact blocked all RyR channel activity in hippocampal neurons, a challenge of 4CmC [previously shown to activate RyR1 and RyR2, but not RyR3, channel activity (Fessenden et al.