The parents noticed he had a yellowish skin color and visited their pediatrician who ordered liver function tests: S-bilirubin, aspartate aminotransferase (S-AST), alanine aminotransferase (S-ALT), and S-ALP
. The S-bilirubin, AST, ALT were all normal, but the S-ALP
was significantly elevated (80 [micro]kat/L; normal 2.5-9.5 [micro]kat/L).
Normal levels of S-BGP but increased S-ALP suggested increased formation inadequately compensating for resorption (Table I).
Bone indices: The level of S-ALP was significantly (p < 0.05) higher in the three men with osteoporosis (cases 2, 4 and 5, Table I).