S2


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AcronymDefinition
S2Sims 2 (game)
S2Socom 2 (gaming)
S2Intelligence Officer (US Army)
S2Super Solenoid (Evangelion)
S2Smackdown 2 (Playstation game)
S2Intel Office (USMC)
S2Shut Up and Sit Down
S2Sleep Mode 2 (partial-sleep computer power-down state)