SAXSSmall Angle X-Ray Scattering
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With biological samples like proteins and DNA, the relatively simple sample preparation means that SAXS can provide important structural information about these molecules in a more natural environment.
Prices for SAXS systems vary a great deal depending on the X-ray source, X-ray optics and detector used in a system.
Other parameters of interest obtainable from SAXS are the number of crystals in a stack, the orientation of the crystal stacks, and, in cases where the absolute intensity of scattering is known, the percentage crystallinity of the polymer.
For polymers oriented by drawing at elevated temperatures, or for melt-spun polymeric fibers, SAXS typically displays a two-point scattering pattern, indicative of alignment of crystals with their normals parallel to draw direction.
The N8 HORIZON follows the Bruker philosophy of combining high technical sophistication with ease-of-use, and will bring SAXS beyond the expert level into the standard laboratory," stated Dr.
The N8 HORIZON perfectly fits into our successful Bruker SAXS portfolio, as this new system will further strengthen Bruker's position as the leading SAXS company by expanding the market potential into applications which never used SAXS before," commented Professor Dr.
SAXS can provide information on: particle size and size distribution; particle shape (sphere, cylinder, lamella) and internal structure (core-shell); porosity (surface-to-volume ratio); order (crystallinity) and orientation of the particles; and molecular weight and aggregation number.
In a SAXS experiment the sample is irradiated by an x-ray beam.
The goal of this collaboration is to develop a set of integrated SAXS and NMR data analysis algorithms for determining the structures of larger multi-domain proteins and protein complexes with DNA, RNA or other proteins.
The SAXS Pair Distance Function (PDF) of Urate Oxidase from Aspergillus Flavus (PDB 1R56) describes the radial distribution of density in the molecule which provides global constraints on the overall size and shape of the molecule for the local NMR coordinate measurements.
The next generation platform offers significantly improved cost of ownership and higher throughput; improved ease of use and extendibility; and the addition of the SAXS capability for measurement of pore size and distribution of low-k dielectrics, capable of determining pore diameters down to sub-10 angstrom.
Phase II will evaluate fast Wide Angle micro-XRD (WAXRD) as a stand alone metrology tool or as integrated channel with Jordan Valley's XRR and SAXS channels, making it an integrated total solution tool for Cu process ramp up and control.