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Experimental Concept: Generally, serum SCCA2 content was tested for overall SCCA analysis.
Peripheral bloods were collected, and the SCCA2 contents were detected by SCCA2 ELISA kit, with the values Greater than 1.
Table-I: Relative expression rates of SCCA1 and SCCA2 before treatment.
Relative Expression Rates of SCCA1 and SCCA2 before Treatment: The two groups had similar relative SCCA1 expression rates (P Greater than 0.
Relative SCCA2 Expression Rate and Correlated Factors: Relative SCCA2 expression was significantly correlated with lymphatic metastasis, T classification and clinical stage.
SCCA2 Expressions after Treatment: Fifty-three patients were treated effectively by chemotherapy, while the 23 patients were not.
In contrast, relative SCCA2 expression rate can be used as a specific tumor marker because it was higher in the patients with lymphatic metastasis, as was lower in those with later clinical stage.
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- SCC H/N
- SCC Network Interface
- SCCA2/SCCA1 fusion protein