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The two noninvasive indices, SCCAI and Seo, correlated well with the invasive St.
Two out of these 16 patients had a SCCAI score of > 2.5 at the time of the second endoscopy.
In our study of patients achieving f-calprotectin < 250 [micro]g/g and with endoscopic mucosal healing, there were still two patients with SCCAI > 2.5.
Crohn's Ulcerative disease colitis (CD) (UC) Number of patients, n 7 4 Age mean 45,3 47,5 Disease activity mean (range): HBI 5 (2-10) -- SCCAI -- 1 (0-2) Location, n L1: 2 E1: 3 L2: 5 E2:1 L3: 2 E3: 0 L4: 0 Behaviour of CD, n B1: 5 -- B2: 1 B3: 1 Treatment, n: Steroid treatment 0 0 Immunosuppressive treatment 3 1 Biologics treatment 3 1 5 ASA 1 3 None 1 0 Occupation, n: Work parttime 2 1 Work full time 4 2 Retired 1 0 Sick-listed 0 1 Relationship, n: Living with partner only 1 0 Living with partner and children 4 3 Living with children only 2 1 Living alone 0 0 HBAI: Harvey Bradshaw Activity Index.
Abbreviations BMI: Body mass index CD: Crohn's disease CI: Confidence interval GI: Gastrointestinal HADS: Hospital anxiety and depression scale HBI: Harvey-Bradshaw index HR: Hazard ratio IBD: Inflammatory bowel disease PHQ-15: Patient health questionnaire-15 RCT: Randomised controlled trial SCCAI: Simple clinical colitis activity index SNRI: Serotonin and noradrenaline reuptake inhibitor SSRI: Selective serotonin reuptake inhibitor TCA: Tricyclic antidepressant UC: Ulcerative colitis.
The proportion of patients who had a clinical response (defined as a reduction of at least 3 points in the SCCAI score) was also significantly higher in the curcumin group than in the placebo group (65.3% vs.
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