SECISSelenocysteine Insertion Sequence
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GPxs include enzymes with or without the SECIS element, corresponding to a SEC or a Cys residue in the active site of the proteins, respectively.
2005), we assessed readthrough of the UGA codon [with appropriate selenocysteine insertion sequence (SECIS) element in the sense configuration] when COS7 cells were treated with arsenite.
The hSECIS/S (SECIS element in the sense orientation) reporter gene fusion was transfected into COS7 cells, and 3 hr after transfection (in serum-containing medium), arsenite was added at a concentration of 4 [micro]M.