SELDI-TOFSurface-Enhanced Laser Desorption/Ionization Time-Of-Flight
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SELDI-TOF MS was performed according to the manufacturer's instructions with some previously described modifications [7].
Urine screening by Seldi-Tof, followed by biomarker identification, in a Brazilian cohort of patients with renal cell carcinoma (RCC).
For the SELDI-TOF study, the sample set from a former investigation was used [21].
Coombes, "Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments," Bioinformatics, vol.
One group of researchers reported that, using protein chip arrays and SELDI-TOF, they identified a panel of five proteins whose expression was significantly altered in AD patients compared with healthy control subjects (Carette et al.
Clinical proteomics: searching for better tumour markers with SELDI-TOF mass spectrometry.
As an example, in one recent study, results derived from the serum analyses from 76 patients with breast cancer and 54 unaffected women were analyzed by two-dimensional (2-D) electrophoresis and matrix-assisted SELDI-TOF. One marker, HSP27, was found up-regulated, while a second (14-3-3 sigma) was down-regulated in the serum of breast-cancer patients.
Habermann, "SELDI-TOF serum proteomics and colorectal cancer: a current overview," Archives of Physiology and Biochemistry, vol.
Proteomics technologies are making progress in detecting low-expression molecules through more sophisticated sorting technologies such as SELDI-TOF (a method that selects only a subset of proteins from a given sample for analysis).
In 2000, MAS accused Ciphergen of committing a breach of agreement after the company sublicensed SELDI-TOF technology from MAS.