To our knowledge, there are few reports of a myopericarditis due to SFGR
infections (Table) (2-9), and in PubMed, we found none attributed to R.
IFA for SFGR
was non-reactive in the patient's serum and CSF.
A skin biopsy specimen of the rash lesion obtained after death and tested by PCR at CDPH was positive for DNA of SFGR
infection was defined as seroconversion or a 4-fold increase in R.
We screened specimens for antibodies against TGR, SFGR
, and STGO by ELISA, as described (11), and determined titers for positive specimens.
burnetii and SFGR
cases were detected throughout the year, with peaks noted in February-June for SFGR
and April-July for C.
ticks are active in central Spain), we have further epidemiologic evidence for attributing the infection to SFGR
The chance of a soldier having an infection with SFGR
was significantly higher than the chance of having an infection with TGR or STGO ([chi square] test, p<0.
We tested for molecular evidence of any SFGR
species by nested PCR of rompA (rickettsial outer membrane protein A gene) (1).
The increase in convalescent-phase geometric mean titer was 14-fold (845) for SFGR
, 17-fold (920) for TGR, and 11-fold (951) for SFGR
rickettsii, consistent with previous surveys of this tick for SFGR
in North Carolina and other states (8,14,15).
Immunohistochemical staining for SFGR
showed rare antigens in a few small foci of perivascular inflammation.