SIAHSeven in Absentia Homolog
SIAHsyndrome of inappropriate antidiuretic hormone (also seen as SIADH)
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It is likely to move into the clinical setting for study as an interventional treatment in pancreatic cancer in human patients," Tang said, referring to the SIAH inhibition.
She said that, in humans, the SIAH ubiquitin ligases sit smack in the middle of the molecular pathway that leads to pancreatic cancer.
Her team found that SIAH ubiquitin ligases were specifically and markedly "upregulated" in pancreatic cancers.