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During high pollen season, the mean SIGH-SAD score for those in the allergen-specific IgE-positive group who had typical depression was 11.
The SIGH-SAD score was also higher for those in the allergen-specific IgE-positive group who had atypical depression (a mean of 6.
The SIGH-SAD, which emphasizes somatic symptoms, found combination therapy to be most effective, but when outcome was defined by BDI-II, which focuses on cognitive, behavioral, and affective elements of depression, CBT alone fared best.