As a result, treatment was changed to belimumab which achieved an excellent response characterized by a normalization of complement levels, a reduction in anti-ds-DNA ab and SLEDAI
values, and a nearly complete resolution of the patient's clinical manifestations (9).
Disease activity was calculated using SLEDAI
was not different in the two groups.
The mean SLEDAI
in 26 such admissions in 12 patients was 10.58.
The median SLEDAI
score of these SLE patients was 9 (6, 12), and the actual median dose of corticosteroids was 15 (10, 45) mg/d.
The patients from the SLE group were all women and the median of the SLEDAI
was 12 (Table 1).
In our study, only nine patients had high activity of the disease according to the SLEDAI
The inclusion criteria were patients diagnosed as SLE based on the criteria of American College of Rheumatology (ACR) 1997, active SLE (SLEDAI
> 3), and 25(OH)D level < 30 ng/ml.
in 2013 described another cohort of five patients with SLE presenting with PRES, all of which had hypertension and moderate-to-severe SLEDAI
disease activity .
The SLE Disease Activity Index (SLEDAI
) was used for the assessment of disease activity.
Systemic lupus erythematosus disease activity index (SLEDAI
) was 5 points which indicated that SLE was flare.
Clinical and biological data of individual patients were collected, including age, sex, hematological changes, anti-double stranded deoxyribonucleic acid (anti-dsDNA) antibody titers, plasma C3 levels and Systemic Lupus Erythematosus Disease Activity Index (SLEDAI