whether a patient who had a positive SLNB
prior to NACT could have a repeat SLNB
after NACT to increase the rate of axillary preservation?
Because many patients now present with clinically nodenegative disease, SLNB
can identify those with proven nodepositive disease who may benefit from complete axillary dissection.
2], the guidelines recommend that physicians "discuss and consider" SLNB
, which the available evidence suggests has roughly a 7% pretest probability of a positive result.
Neurological examination was negative, and 10 trials of SLNB
15) The NCCN also recommends radiation therapy to the primary site alone in cases of a negative SLNB
result, and it recommends radiation therapy to both the primary site and the draining lymph nodes in cases of a positive SLNB
result or cN+ disease.
Although often performed in the USA, it is generally agreed that SLNB
provides important prognostic information but does not confer a survival benefit in patients with cutaneous melanoma .
Key to the new approach is the use of sentinel lymph node biopsy (SLNB
) performed as an outpatient procedure a week or so prior to mastectomy, rather than doing the SLNB
at the same operation as the mastectomy and reconstruction.
5% (n=3) following SLNB
and the difference was found statistically significant (p=0.
The reason SLNB
is of less use than with other melanomas is that DM "doesn't often spread through the lymphatics.
Abbreviations: ALND, axillary lymph node dissection; BCS, breast-conserving surgery; ECE, extracapsular extension; FS, frozen section; pN1, macrometastatic disease; pN1mi, micrometastatic disease; RT, radiotherapy; SLN, sentinel lymph node; SLNB
, sentinel lymph node biopsy.
Objective: To look into the pattern of breast cancer recurrence following mastectomy, breast conservative surgery and radiotherapy or chemotherapy after SLNB
at our institution.