In 2014, the American Society of Clinical Oncology (ASCO) published updated guidelines regarding SLNB
for patients with early-stage BC.
Meric-Bernstam et al., "Trends in and outcomes from sentinel lymph node biopsy (SLNB
) alone vs.
The sensitivity of SLNB
for node involvement ranges from 71 % to 100%, and the false-negative rate averages 8.4%, ranging from 0% to 29% across all studies .
Among these patients, 166 (76.1%) had a history of smoking, 118 (54.1%) underwent mastectomy, 100 (45.9%) underwent breast conserving surgery (BCS), 131 (60.1%) underwent standard level I--II AD due to positive sentinel lymph node(s), 87 (39.9%) underwent SLNB
The term micrometastasis has been replaced by "clinically occult disease" as detected by SLNB
. Macrometastasis has been supplanted by "clinically detected disease." And while in-transit or satellite node metastasis or microsatellite metastasis with satellite nodes was formerly listed simply as N3, in the new system there are subcategories for N3 based upon the number of metastatic nodes involved.
If USG detects axillary metastasis, the SLNB
can be omitted and ALND can be performed directly.
The concept of SLNB
in breast cancer was introduced in the 1990s and 10 year follow-up of these data showed it to be a safe alternative to full axillary node dissection.
The patient is placed in the semi-lateral decubitus position, and the incision performed for SLNB
or ALND is slightly extended laterally in order to find the lateral edge of the latissimus dorsi muscle.
Various studies have been documented in literature related to SLNB
in breast cancers.
technique has not been internationally standardized, and the methods and materials used for the procedure vary among surgeons and institutions.
After a detailed discussion with the patient, sentinel lymph node biopsy (SLNB
) and excision were elected and performed.
(2) Sentinel lymph node biopsy (SLNB
) is the standard management approach for regional node metastasis.