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The popularity of common ancillary tests, including EEG, SLSEP, and TCD, has significantly improved since 2013 with the help of the BQCC's training program.
Therefore, the BQCC still recommends that EEG and SLSEP should be performed as electrophysiological tests to determine brain death, and TCD should be performed as a technique for the detection of cerebral blood flow for brain death determination.
In a 2013 meta-analysis (12 studies, 1058 patients), during or after rewarming from hypothermia, the FPR was 0 (95% CI : 0.00–0.02, 95% CI : 0.00–0.04, respectively) for poor outcomes associated with the bilateral absence of the N20 response of SLSEP [sup] (Evidence Class I).
During hypothermia (32–34[degrees]C), predictors of poor prognosis in comatose patients with hypothermia treatment include the bilateral absence of the N20 response of SLSEP (Recommendation Level A, Evidence Class I), the highest threshold of the NSE (24 h ≥52.4 [micro]g/L) or S-100B (24 h ≥0.18–0.21 [micro]g/L) protein serum concentration (Recommendation Level A, Evidence Class I), and a BIS value of 0 in QEEG (Recommendation Level B, Evidence Class II).
(13) SLSEPs are widely used in clinical practice, because they are rarely influenced by consciousness and have explicit neural origins.
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