SLVDSSan Luis Valley Diabetes Study
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Between 2006 and 2008, study subjects or next of kin of deceased subjects as designated in SLVDS (14.2%) were contacted by mail with information about the study, followed by a call to set up an appointment for an interview and water sample collection.
The wide spectrum of longitudinal clinical, behavioral, and demographic data in SLVDS, plus a low rate of out-migration, along with variability in inorganic arsenic exposure in the San Luis Valley, renders this region and cohort particularly suitable for this research.
We believe that misclassification bias would be small given the low migration of this population [5% migrated to the SLV as children, and only 10 participants (war veterans) lived outside of the SLV for > 6 months (< 3 years) through 1998] and the validation of clerk records and SLVDS database to complete residential history.