SMURF1SMAD Ubiquitination Regulatory Factor 1
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Also, genome screening studies have identified additional PINK1/Parkin regulators like SMURF1 (SMAD specific E3 ubiquitin protein ligase 1), ATPIF1/IF1 (ATPase inhibitory factor 1), and TOMM7 which, likely, promote autophagy [224-226].
53-57) For example, novel candidate oncogenes include SMURF1 on 7q21, FGFR1 on 8p12, BIRC2 and BIRC3 on 11q22, and PAK4 on 19q13, whereas novel candidate tumor suppressor genes include TUSC3 on 8p22 and FEZ1 on 8p23.