SNCCLSmall Non-Cleaved Cell Lymphomas
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Because of the cohesive nature of the neoplastic cells with a squared-off appearance in combination with high numbers of mitotic figures and numerous apoptotic bodies and tingible body macrophages, PBL can also be confused with Burkitt/small non-cleaved cell lymphoma (SNCCL), which is another common AIDS-related subtype of non-Hodgkin lymphoma.[11] In addition to some similar morphologic features, both PBL and SNCCL in HIV-positive patients are typically associated with EBV.